Which one? 😃
I started as a player in the original LA by Fire, took on an assistant ST position, and then eventually took over as head ST. At its height, that game had... close to 30 players. That game was an ST gristmill and eventually it chewed through all the STs that were willing to run it. So it pretty much collapsed under its own weight.
I rebooted LA by Fire sometime during season 18 of the podcast, and that's probably the game to which you're referring. In the original game, all of the elders and Primogen and court officers were PCs, as well as were all the neonates. A lot of drama was created by elder PCs "bossing around" neonate PCs, even though neonate PCs outnumbered the elders by like... 3:1 or more. I wanted to do away with all that drama, so I made the reboot a neonate game, with all the elders and Primogen and court offices as NPCs. It sounded like a good idea, and was fine with a low PC count, but when the game got up to, you know, 15 or so players - all wanting individual NPC time to deal with Kindred society stuff - it, too, fired up the gristmill and started feeding me in. I brought in another ST, backed off a bit to catch my breath, and the game imploded.
V:tM games run as a PbP sandbox are an extreme challenge with many players. But! They're also very awesome, and they're the carrot that I keep chasing. I'm actually trying to start up another one - with mechanics and rules to support what I've learned from the first two - but I haven't been able to recruit enough players.